منابع مشابه
5-fluorouracil 0.5% cream for multiple actinic or solar keratoses of the face and anterior scalp.
Carac (5-fluorouracil 0.5% cream, Aventis Pharma) was approved by the US FDA in October 2000, for the treatment of multiple actinic or solar keratoses involving the face and anterior scalp. The cream should be applied in a thin film once daily to the skin where actinic keratoses (AKs) are present. When it is applied for 1, 2, or 4 weeks, it is significantly more effective than a vehicle in the ...
متن کاملPolymorphisms of the VDR gene are associated with presence of solar keratoses on the skin.
BACKGROUND Vitamin D has a range of biological effects including antiproliferative functions that are mediated through its receptors, encoded by the VDR gene. OBJECTIVES We investigated polymorphisms within the VDR gene for association with solar keratosis (SK), a biomarker for skin cancer, and examined interactions with skin phenotype. METHODS Among participants of the community-based Namb...
متن کاملDifference in histological subtypes of basal cell carcinoma according to age, gender, location, mitotic activity and association with solar keratoses
Background and aim: Basal cell carcinoma (BCC) is the most common skin cancer in white-skin populations. Recent studies suggest that BCC is not a single entity and different histological subtypes show different clinical behavior and might have different etiology. The aim of this study was to assess differences in age, sex, site of distribution and proliferative activity in histological subtypes...
متن کاملPolymorphism of glutathione S-transferases M1 and T1: susceptibility to solar keratoses in an Italian population.
BACKGROUND Polymorphisms of glutathione S-transferases (GSTs) are linked to skin cancer, but data on their association with solar keratosis (SK) are few and conflicting. AIM To verify the possible association between the development of SK and the 'null' GSTM1 and/or T1 genotype. METHODS Analysis of the GSTM1 and T1 genotype of 33 subjects with ≥3 solar keratoses and of 150 controls, before ...
متن کاملChromosomal aberrations in squamous cell carcinoma and solar keratoses revealed by comparative genomic hybridization.
OBJECTIVE To identify chromosomal copy numbers of frequent genetic aberrations within squamous cell carcinomas (SCCs) and solar keratoses (SKs), and provide further evidence to support or challenge current dogma concerning the relationship between these lesions. DESIGN Retrospective analysis of genetic aberrations in DNA from SK and SCC biopsy specimens by comparative genomic hybridization. ...
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ژورنال
عنوان ژورنال: Archives of Dermatology and Syphilology
سال: 1920
ISSN: 0096-6029
DOI: 10.1001/archderm.1920.02350020058006